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Table 1 Genotype frequencies of the deletion (del)/insertion (ins) polymorphism of 30 Kb on chromosome 7p11 amongst the four patient groups

From: PSPHL and breast cancer in African American women: causative gene or population stratification?

 

Del/Del

Ins/Del

Ins/Ins

P-value

AA case

0.06 (n = 12)

0.35 (n = 70)

0.59 (n = 117)

 

C case

0.62 (n = 362)

0.34 (n = 202)

0.04 (n = 25)

P < 0.0001a

AA controls

0.04 (n = 13)

0.31 (n = 112)

0.65 (n = 235)

P = 0.211b

C controls

0.64 (n = 232)

0.34 (n = 123)

0.02 (n = 9)

P = 0.336c

  1. AA = African American, C = Caucasian.
  2. aP-value calculated between African American and Caucasians with invasive breast cancer.
  3. bP-value calculated between African American cases and controls.
  4. cP-value calculated between Caucasian cases and controls.