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Table 2 Description of lead SNPs showing significant association with hematological traits by GWAS

From: Genome-wide association studies for hematological traits in Chinese Sutai pigs

Traits1 Peak SNP Num2 Chr3 Pos (bp)4 Nearest gene5 Distance (bp)6 P-value Var (%)7
MCV** ss478944677 75 2 55226096 SH3BP5L Within 3.00E-11 19.41
MCH** ss131190955 60 2 60227081 CPAMD8 Within 1.36E-10 7.91
RDW** ss107831331 14 2 70061497 CARM1 Within 2.10E-07 14.13
MCHC* ss131046473 22 6 49168322 ELSPBP1 65 1.52E-06 10.06
HCT* ss131276048 5 4 104825883 INTS3 Within 3.19E-06 6.80
RBC* ss131276048 4 4 104825883 INTS3 Within 3.78E-06 6.52
HGB* ss131493776 1 13 11696883 UBE2E1 Within 7.88E-06 4.75
WBC* ss107857076 2 2 105499649 ENSSSCG00000030166 95033 6.03E-06 8.66
P-LCR** ss107886044 17 2 56469735 TRIM58 Within 1.58E-07 13.32
MPV* ss107886044 5 2 56469735 TRIM58 Within 2.49E-06 15.43
  1. The associated region was defined as the interval the distances between two adjacent genome-wide significant SNPs was less than 10 Mb.
  2. 1The abbreviations of hematological traits are given in Table 1. e.g. MCV is Mean corpuscular volume.
  3. 2The number of significant SNPs for each hematological trait.
  4. 3, 4Chromosomal locations and positions of the most significant SNP associated with hematological traits in Sus scrofa Build 10.2 assembly.
  5. 5The nearest annotated gene to the significant SNP. The annotated gene database is from http://asia.ensembl.org/index.html.
  6. 6SNP designated as in a gene or distance (bp) from a gene region in Sus scrofa Build 10.2 assembly, “0” in column 6 represent un-annotated genes.
  7. 7the phenotype variance explained by the significant SNP.
  8. **Genome-wide significant.
  9. *Chromosome-wide significant.