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Table 6 Estimated 5% genome-wide significance threshold from 10 000 null simulations

From: Effect of advanced intercrossing on genome structure and on the power to detect linked quantitative trait loci in a multi-parent population: a simulation study in rice

  

Number of cycles

  

0

1

2

4

6

8

10

12

20

22

8-way IRIPs (n = 800)

T 1

4.03

4.03

4.09

4.2

4.11

4.1

4.22

-

4.23

-

T 2

4.74

4.81

4.86

4.95

4.97

4.87

5.03

-

5.19

-

T 2vs1

2.45

2.47

2.34

2.3

2.23

2.16

2.26

-

2.32

-

2-way IRIPs (n = 200)

T 1

4.09

-

4.02

4.15

4

4.11

4.15

4.19

-

4.15

T 2

4.99

-

5.17

5.25

5.2

5.28

5.38

5.43

-

5.43

T 2vs1

2.98

-

2.93

2.69

2.67

2.51

2.44

2.4

-

2.23

2-way IRIPs (n = 800)

T 1

4.00

-

3.90

3.82

3.86

3.67

4.22

4.02

-

4.10

T 2

4.61

-

4.44

4.46

4.73

4.22

5.21

4.92

-

4.75

 

T 2vs1

2.82

-

2.81

2.73

2.44

2.18

2.66

2.42

-

2.06

  1. T1 represents the thresholds for the single-QTL model. T2 represents the thresholds for the two-QTL model, and T2vs1 represents the thresholds if whether the two-QTL model provides a sufficiently improved fit over the best single-QTL model to justify its use.