Table 1 Incidence of testicular tumors and testicular abnormalities in the congenic strains
Mouse strains | % TGCTs | No. with TGCT | % (no.) unilateral TGCTs | % (no.) bilateral TGCTs | % (no.) abnormal testes | No. of males examined |
|---|---|---|---|---|---|---|
*129 | 5% | 4 | 5% (4) | 0 | 15% (12) | 83 |
*M19 | 71% | 85 | 39% (46) | 33% (39) | 5% (6) | 119 |
Single congenics | ||||||
5 | 4% | 4 | 3% (3) | 1% (1) | 24% (23) | 96 |
6 | 19% | 25 | 16% (21) | 3% (4) | 26% (35) | 134 |
*3 | 32% | 26 | 21% (18) | 10% (8) | 9% (7) | 82 |
*B-81 | 4% | 5 | 4% (5) | 0 | 10% (13) | 129 |
7 | 14% | 18 | 12% (16) | 2% (2) | 5% (7) | 133 |
Double congenics | ||||||
5 × 3 | 34% | 47 | 26% (35) | 9% (12) | 12% (17) | 137 |
5 × B-81 | 11% | 14 | 9% (12) | 2% (2) | 16% (21) | 133 |
5 × 7 | 8% | 11 | 8% (10) | 1% (1) | 14% (18) | 130 |
6 × B-81 | 10% | 9 | 10% (9) | 0 | 15% (13) | 88 |
1 | 22% | 38 | 20% (35) | 2% (3) | 6% (10) | 171 |
3 × 7 | 26% | 32 | 18% (22) | 8% (10) | 11% (13) | 122 |
Triple congenic | ||||||
5 × 3× 7 | 37% | 50 | 30% (40) | 7% (10) | 8% (11) | 136 |