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Table 4 Laterality of TGCTs in the congenic strains

From: Tumor loci and their interactions on mouse chromosome 19 that contribute to testicular germ cell tumors

Congenic strain No. of males examined   No TGCT Unilateral left tumor Unilateral right tumor Bilateral tumors Test score Left/Right
5 96 Observed 92 2 1 1 8.76, P < 0.04 1.5
   Expected 91.3 2.8 1.9 0.1   
6 134 Observed 109 17 4 4 7.36, ns 2.7
   Expected 105.8 20.2 6.8 1.3   
3 82 Observed 56 10 8 8 8.97, P < 0.03 1.1
   Expected 51.2 14.4 12.8 3.6   
7 133 Observed 115 13 3 2 3.97, ns 2.8
   Expected 113.6 14 4.7 0.6   
5 × 3 137 Observed 90 20 15 12 8.37, P < 0.04 1.2
   Expected 84.4 25.2 21.1 6.3   
5 × B-81 133 Observed 119 8 4 2 5.73, ns 1.6
   Expected 116.2 10.1 6.1 0.5   
5 × 7 130 Observed 119 7 3 1 3.38, ns 2.0
   Expected 118.5 7.6 3.7 0.2   
6 × B-81 88 Observed 79 9 0 0 0, ns All left
   Expected 79.2 8.8 0 0   
1 171 Observed 133 26 9 3 0.63, ns 2.4
   Expected 132 27 9.9 2   
3 × 7 122 Observed 90 12 10 10 16.98, P < 0.001 1.1
   Expected 84 18.4 16 3.5   
5 × 3 × 7 136 Observed 86 33 7 10 6.34, ns 2.5
   Expected 80.5 37.9 12 5.7   
  1. ns = no statistically significant difference. Higher than Expected levels of Observed bilateral tumors are indicated in green.