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Table 4 Laterality of TGCTs in the congenic strains

From: Tumor loci and their interactions on mouse chromosome 19 that contribute to testicular germ cell tumors

Congenic strain

No. of males examined

 

No TGCT

Unilateral left tumor

Unilateral right tumor

Bilateral tumors

Test score

Left/Right

5

96

Observed

92

2

1

1

8.76, P < 0.04

1.5

  

Expected

91.3

2.8

1.9

0.1

  

6

134

Observed

109

17

4

4

7.36, ns

2.7

  

Expected

105.8

20.2

6.8

1.3

  

3

82

Observed

56

10

8

8

8.97, P < 0.03

1.1

  

Expected

51.2

14.4

12.8

3.6

  

7

133

Observed

115

13

3

2

3.97, ns

2.8

  

Expected

113.6

14

4.7

0.6

  

5 × 3

137

Observed

90

20

15

12

8.37, P < 0.04

1.2

  

Expected

84.4

25.2

21.1

6.3

  

5 × B-81

133

Observed

119

8

4

2

5.73, ns

1.6

  

Expected

116.2

10.1

6.1

0.5

  

5 × 7

130

Observed

119

7

3

1

3.38, ns

2.0

  

Expected

118.5

7.6

3.7

0.2

  

6 × B-81

88

Observed

79

9

0

0

0, ns

All left

  

Expected

79.2

8.8

0

0

  

1

171

Observed

133

26

9

3

0.63, ns

2.4

  

Expected

132

27

9.9

2

  

3 × 7

122

Observed

90

12

10

10

16.98, P < 0.001

1.1

  

Expected

84

18.4

16

3.5

  

5 × 3 × 7

136

Observed

86

33

7

10

6.34, ns

2.5

  

Expected

80.5

37.9

12

5.7

  
  1. ns = no statistically significant difference. Higher than Expected levels of Observed bilateral tumors are indicated in green.