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Table 2 Type 1 error comparisons for different approaches at the 0.05 level of significance for 1000 replicates, each replicate representing a data set containing 1000 cases and 1000 controls

From: Calculation of exact p-values when SNPs are tested using multiple genetic models

Method

α =0.05

Additive Only

0.044

Dominant Only

0.045

Recessive Only

0.056

Min-p

0.105

Bonferroni

0.030

Exact p-value

0.047

  1. Min-p: p-value based on reporting the smallest p-value of the three genetic models.
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BMC Genomic Data

ISSN: 2730-6844

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