SLC6A4STin2 VNTR genetic polymorphism is associated with tobacco use disorder, but not with successful smoking cessation or smoking characteristics: a case control study

Table 2 STin2 VNTR polymorphism in patients with tobacco use disorder (TUD) versus never-smokers

STin2 VNTR		Never-smokers n = 175		TUD n = 185		OR	95% CI	χ ²	p
		Yes	No	Yes	No
Genotypes	STin2 - 12/12	72	103	82	103	0.88	0.58-1.33	0.54	0.372
	STin2 - 12/10	50	125	71	114	1.56	1.00-2.42	3.88	0.049
	STin2 - 12/9	3	172	6	179	0.63	0.15-2.67	0.72	0.353
	STin2 - 10/10	49	126	26	159	0.42	0.25-0.71	10.60	< 0.001
	STin2 - 10/9	0	175	0	185	-	-	-	-
	STin2 - 9/9	1	174	0	185	-	-	-	-
Allelic Variants	STin2.12	125	50	159	26	2.45	1.44-4.15	11.38	< 0.001
Allelic Variants	STin2.10	99	76	97	88	0.85	0.56-1.28	0.621	0.431
	STin2.9*	4	171	6	179	1.43	0.40-5.17	-	0.751

OR: odds ratio with 95% CI: confidence interval). All results of χ² tests (df = 1), except * result of Fisher exact probability test.

ISSN: 2730-6844