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Table 1 Histotype and staging parameters associated with the MMP phenotype in our GCsa

From: Somatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotype

Variable Number of patients P valueb
  Total (%) MMP+ (%) MMP-(%)  
Histotype     
   Intestinal 32(68.0) 12(37.5) 20(62.5)  
   Diffuse + Mixed 15(32.0) 3(20.0) 12(80.0) NSc
T (depth of wall infiltration)     
   T1 + T2 12(25.5) 6(50.0) 6(50.0)  
   T3 + T4 35(74.5) 9(25.7) 26(74.3) NS
N (lymph node status)     
   N0 18(38.3) 11(78.5) 7(21.5)  
   N+ 29(61.7) 4(12.1) 25(87.9) = 0.001
M (metastases)     
   M0 40(85.1) 14(35.0) 26(65.0)  
   M+ 7(14.9) 1(14.2) 6(85.8) NS
Staging     
   I + II 20(42.5) 10(58.8) 10(41.2)  
   III + IV 27(57.5) 5(16.6) 22(83.4) = 0.02
Totala 47 15 32  
  1. a – data were available for 47 out of 50 cases b – at Fisher exact test c – NS = not statistically significant