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Table 1 Transmission of alleles of the codon 17 dimorphism at the CTLA4 locus from heterozygous parents to affected probands in 56 discordant sibling pairs with IDDM

From: CTLA4 gene polymorphisms are associated with, and linked to, insulin-dependent diabetes mellitus in a Russian population

Allele

TDT

Combined (TDT + S-TDT)

 

Transmitted

Not transmitted

χ2a (df = 1)

P value

z'

P Value

Ala

39

11

15.680

0.00008

4.072

0.00003

Thr

11

39

15.680

0.00008

4.072

0.00003