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Table 2 Transmission of alleles of the (AT)n polymorphic marker at the CTLA4 locus from heterozygous parents to affected probands in 56 discordant sibling pairs with IDDM

From: CTLA4 gene polymorphisms are associated with, and linked to, insulin-dependent diabetes mellitus in a Russian population

Allele

TDT

Combined (TDT + S-TDT)

length, bp

Transmitted

Not transmitted

χ2a

P value

z'a

P value

11

0

2

    

12

1

1

    

13

4

9

    

14

1

0

    

15

9

5

    

16

14

9

    

17

21

4

11.560

0.0112

3.200

0.00112

18

7

2

    

19

1

2

    

20

2

14

9.000

0.0405

2.750

0.045

21

12

4

    

24

9

10

    

25

2

1

    

26

2

21

15.696

0.0017

3.956

0.00068

27

0

1

    

29

1

1

    

30

1

1

    
  1. a Only χ2 (df = 1) and z' values for which P < 0.05 are indicated
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BMC Genomic Data

ISSN: 2730-6844

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