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Table 2 Transmission of alleles of the (AT)n polymorphic marker at the CTLA4 locus from heterozygous parents to affected probands in 56 discordant sibling pairs with IDDM

From: CTLA4 gene polymorphisms are associated with, and linked to, insulin-dependent diabetes mellitus in a Russian population

Allele TDT Combined (TDT + S-TDT)
length, bp Transmitted Not transmitted χ2a P value z'a P value
11 0 2     
12 1 1     
13 4 9     
14 1 0     
15 9 5     
16 14 9     
17 21 4 11.560 0.0112 3.200 0.00112
18 7 2     
19 1 2     
20 2 14 9.000 0.0405 2.750 0.045
21 12 4     
24 9 10     
25 2 1     
26 2 21 15.696 0.0017 3.956 0.00068
27 0 1     
29 1 1     
30 1 1     
  1. a Only χ2 (df = 1) and z' values for which P < 0.05 are indicated