Table 1 Observed PPARγ Genotype and allele frequencies and their association with BMI in the Tayside type 2 diabetic population.
Polymorphism | Type 2 Diabetic | BMI | SD | p | |
|---|---|---|---|---|---|
Pro12Ala | Pro/Pro | 869 | 30.7 | 6.0 | |
Pro/Ala | 227 | 31.2 | 6.9 | 0.3 | |
Ala/Ala | 11 | 32.9 | 6.2 | ||
Total | 1107 | ||||
Allele frequencies | Pro | 0.888 (0.874–0.901) | |||
Ala | 0.112 (0.099–0.126) | ||||
C1431T | C/C | 852 | 30.6 | 5.7 | |
C/T | 248 | 31.6 | 6.8 | 0.5* | |
T/T | 8 | 32.3 | 3.8 | ||
Total | 1107 | ||||
Allele frequencies | C | 0.882 (0.868–0.895) | |||
T | 0.119 (0.106–0.133) |