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Table 1 Simulation conditions for a binary phenotype, two marker loci M1 and M2, a single locus (Q), sample sizes n = 100, 500, recombination fraction and , respectively, and effect size. * = = 0.0 not simulated

From: Intersection tests for single marker QTL analysis can be more powerful than two marker QTL analysis

Population n Effect Size Number of combinations
Backcross 100, 500 0.0*, 0.10, 0.20, 0.30, 0.40, 0.50 0.0*, 0.10, 0.20, 0.30, 0.40, 0.50 0.40, 0.60, 0.80, 1.00 239*
F 2 500 0.0*, 0.10, 0.20, 0.30, 0.40, 0.50 0.0*, 0.10, 0.20, 0.30, 0.40, 0.50 1.00 25