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Table 1 Simulation conditions for a binary phenotype, two marker loci M1 and M2, a single locus (Q), sample sizes n = 100, 500, recombination fraction and , respectively, and effect size. * = = 0.0 not simulated

From: Intersection tests for single marker QTL analysis can be more powerful than two marker QTL analysis

Population

n

Effect Size

Number of combinations

Backcross

100, 500

0.0*, 0.10, 0.20, 0.30, 0.40, 0.50

0.0*, 0.10, 0.20, 0.30, 0.40, 0.50

0.40, 0.60, 0.80, 1.00

239*

F 2

500

0.0*, 0.10, 0.20, 0.30, 0.40, 0.50

0.0*, 0.10, 0.20, 0.30, 0.40, 0.50

1.00

25