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Table 3 Haplotype frequencies of PIGR 1093–1739, crude OR and ethnic group adjusted OR.

From: Polymeric immunoglobulin receptor polymorphisms and risk of nasopharyngeal cancer

Haplotype

THAI

CHINESE

TOTAL

ETHNIC GROUP ADJUSTED

 

case

control

case

control

case

control

 

GC frequency

0.556169

0.525147

0.590097

0.447343

0.543478

0.451985

 

OR (95%CI)

1.13(0.76–1.68)

1.18(1.05–3.12)

1.37(1.04–1.79)

1.36(1.02–1.80)

GT frequency

0.148376

0.171968

0.100379

0.234900

0.043478

0.175374

 

OR (95%CI)

0.84(0.49–1.46)

0.35(0.14–0.80)

0.64(0.43–0.93)

0.55(0.37–0.84)

AC frequency

0.280194

0.224853

0.278951

0.286302

0.413043

0.283864

 

OR (95%CI)

1.34(0.85–2.13)

0.95(0.52–1.72)

1.23(0.91–1.66)

1.28(0.93–1.76)

AT frequency

0.015260

0.078032

0.030573

0.031455

0.000001

0.088777

 

OR (95%CI)

0.17(0.04–0.62)

1.10(0.22–4.85)

0.12(0.03–0.40)

0.26(0.09–0.63)

case vs case

 

0.085

     

case vs control

<0.05a

 

<0.05b

 

<0.005c

  

control vs control

 

0.192

     
  1. Each haplotype frequency was calculated by the Estimating Haplotype-frequencies (EH) software program23. Total is Thai, Chinese and Thai-Chinese cases and controls. OR (95%CI) = odd ratios and 95% confidence interval between the tested haplotype and the other three alleles, The OR (95%CI) calculation used the estimated number from each haplotype number of cases and controls. The number of haplotypes in the total category were calculated from the summation of estimated haplotype number from each ethnic. GC, AC, GT, and AT are 1093G-1739C, 1093A-1739C, 1093G-1739T, and 1093A-1739T haplotypes, respectively. Case vs case = p value comparing haplotype frequency between Thai case and Chinese case. Case vs control = p value comparing haplotype frequency between case and control in each ethnic. a is Thai, b is Chinese and c is total. Control vs control = p value comparing haplotype frequency between Thai control and Chinese control.