Using simultaneous equation modeling for defining complex phenotypes

BMC Genomic Data

Table 1 Results of Generalized Linear Models to Determine Structural Equations

		Number of Replicates where the regression coefficient was:
Dependent Variable	Independent Variable	Significant	Not Significant	Normally Distributed?	Mean
Cholesterol	Age ^A	100	0	Yes	0.728
	Cigarettes per day	2	98	Yes	-0.012
	Alcohol consumption	13	87	Yes	0.004
	Glucose	7	93	Yes	0.014
	HDL	10	90	Yes	-0.025
	Height	13	87	Yes	0.008
	Systolic blood pressure	41	59	Yes	0.124
	Sex	43	57	Yes	3.916
	Triglycerides	18	82	Yes	0.020
	Weight	11	89	Yes	0.007
Glucose	Age	14	86	Yes	-0.005
	Cigarettes per day	7	93	Yes	0.001
	Cholesterol	15	85	Yes	-0.016
	Alcohol consumption	100	0	Yes	-0.081
	HDL	95	5	Yes	0.096
	Height	5	95	Yes	-0.007
	Systolic blood pressure	22	78	Yes	0.020
	Sex	90	10	Yes	2.075
	Triglycerides	100	0	No	0.081
	Weight	90	10	Yes	-0.002
HDL-C	Age	100	0	Yes	0.019
	Cigarettes per day	10	90	Yes	-0.003
	Cholesterol	100	0	Yes	0.160
	Alcohol consumption	100	0	No	0.249
	Glucose	95	5	Yes	0.111
	Height	9	91	Yes	0.011
	Systolic blood pressure	10	90	Yes	-0.003
	Sex	100	0	Yes	6.058
	Triglycerides	100	0	Yes	-0.194
	Weight	100	0	Yes	0.047
Tryglycerides	Age	100	0	Yes	1.026
	Cigarettes per day	18	82	Yes	0.012
	Cholesterol	97	3	Yes	0.161
	Alcohol consumption	100	0	Yes	0.997
	Glucose	100	0	Yes	0.573
	HDL	100	0	Yes	-1.163
	Height	8	92	Yes	0.018
	Systolic blood pressure	17	83	Yes	-0.002
	Sex	100	0	No	-17.819
	Weight	100	0	Yes	0.268

ISSN: 2730-6844