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Table 1 Two-point LOD scores for maximum number of cigarettes per day.A

From: Multiple genome-wide analyses of smoking behavior in the Framingham Heart Study

   

Parametric AnalysisD

Variance Components Analysis

ChrB

cMC

Marker

Un- adjusted (θ)

Sex, age adjusted (θ)

Sex, age, year adjusted (θ)

Un- adjusted

Sex, age adjusted

Sex, age, year adjusted

1

167.15

GATA12A07

0.54 (0.3)

0.21 (0.3)

0.37 (0.3)

1.28

0.89

0.44

1

187.86

GGAA5F09

0.57 (0.3)

0.21 (0.3)

0.75 (0.3)

1.46

1.34

0.82

1

193.02

GGAA22G10

0.90 (0.3)

0.44 (0.3)

0.57 (0.3)

1.13

0.94

0.54

2

70.32

ATA4F03

1.98 (0.2)

1.61 (0.2)

0.80 (0.3)

0.04

0.07

0.01

2

100.60

GATA69E12

0.75 (0.3)

0.68 (0.3)

0.69 (0.3)

0.55

1.02

0.99

2

237.47

GATA4G12

0.03 (0.4)

0.00

0.00

0.99

1.09

0.71

7

62.68

GATA31A10

0.08 (0.4)

0.00

0.00

1.10

0.80

0.64

8

24.63

GATA25C10

0.05 (0.4)

0.06 (0.4)

0.02 (0.4)

0.45

0.74

1.04

11

58.51

ATA1B07

0.84 (0.1)

0.74 (0.1)

0.60 (0.2)

0.81

1.10

0.97

12

53.27

ATA27A06

0.00

0.09 (0.4)

0.09 (0.4)

0.20

0.88

1.12

13

83.74

GATA43H03

0.00

0.01 (0.4)

0.58 (0.3)

0.54

0.64

1.06

15

65.52

GATA151F03

0.83 (0.3)

1.09 (0.2)

0.67 (0.3)

0.49

0.21

0.02

17

66.85

GATA25A04

1.52 (0.2)

1.39 (0.2)

0.77 (0.3)

0.81

0.69

0.19

17

138.03

217yd10

0.05 (0.4)

0.12 (0.4)

0.08 (0.4)

1.12

1.35

1.08

20

70.51

GATA47F05

0.82 (0.3)

1.30 (0.2)

1.19 (0.3)

0.36

1.07

1.39

20

84.62

321xd1

0.61 (0.2)

1.02 (0.2)

1.24 (0.2)

0.77

0.95

0.98

  1. AMarkers shown have a LOD = 1. Bold, LOD > 1. BChr, chromosome. CcM, sex-averaged distance from p-term. DParametric LODs are maximized over θ.