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Table 1 Linkage analyses results for mean, slope and baseline measure at Exam 1

From: Genetic analyses of longitudinal phenotype data: a comparison of univariate methods and a multivariate approach

    Multipoint LOD scores at CHCL genes (QTLh2)  
    Slope Genes Baseline Genes  
  No. Subjects Total h2 S7 S8 S9 B30 B31 B32 B33 Number of False Positives (LOD scores)
Baseline 2869 0.55 3.1 (.20) 0.6 0.0 5.3 (.27) 3.1 (.21) 8.1 (.30) 0.0 1 (3.1)
Mean 2812 0.60 10.6 (.33) 1.3 0.0 2 2.8 6.8 (.26) 0.0 1 (3.3)
Slope 2698 0.42 10.3 (.33) 0.25 0.0 0.0 0.0 0.0 0.0 2 (4.3, 3.6)
  1. The table contains number of subjects, total heritability and multipoint LOD scores at slope or baseline CHOL genes; and LOD score peaks ≥ 3 at locations where no CHOL genes existed (false positives) for baseline measure at Exam 1, mean definition 2 and slope. LOD scores in bold indicate genome-wide significant results using LOD = 3 as a threshold. QTL heritabilities for the detected true genes were also presented next to the LOD scores.