Genetic Analysis Workshop 13: Simulated longitudinal data on families for a system of oligogenic traits

Daw, E Warwick; Morrison, John; Zhou, Xiaojun; Thomas, Duncan C

doi:10.1186/1471-2156-4-S1-S3

BMC Genomic Data

Table 2 Effects of genotypes at trait loci.

From: Genetic Analysis Workshop 13: Simulated longitudinal data on families for a system of oligogenic traits

Locus Name	Trait affected			Effect of genotype on trait:
		Variance	Mean	AA	AB	BB	AC	BC	CC	AD	BD	CD	DD
G_b1	HT	0.4	0	-0.907	-0.475	-0.043	0.173	0.605	1.252
G_b2	HT	0.2	0	-0.312	0.088	1.287
G_b3	HT	0.1	0	-0.447	0.000	0.447
G_b4	HT	0.05	0	-0.071	0.077	1.411
G_b5	HT	0.02	0	-0.131	0.087	0.306
G_b6	HT	0.02	0	-0.067	0.267	0.600
G_b7	HT	0.02	0	-0.072	-0.046	-0.020	-0.059	0.186	0.574
G_b8	HT	0.01	0	-0.426	-0.053	0.053
G_b9	HT	0.01	0	-0.169	0.074	0.020
G_b10	HT	0.01	0	-0.038	-0.028	-0.018	-0.033	0.063	0.466
G_b11	WT	0.4	0	-0.564	-0.404	-0.163	1.442	-0.243	-0.002	1.041	0.238	0.640	2.245
G_b12	HDL	0.2	0	-0.464	0.199	0.862
	GLUC	0.05	0	0.232	-0.099	-0.431
	TG	0.1	0	0.328	-0.141	-0.609
G_b13	HDL	0.1	0	-0.195	0.125	0.444	-0.163	0.189	2.106	-0.259	-0.003	-0.514	-0.834
	GLUC	0.1	0	0.243	0.018	-0.545	-0.207	-0.657	-0.770	0.356	0.131	-0.095	0.918
	TG	0.1	0	0.191	-0.123	-0.438	-0.186	-0.312	-0.501	0.506	0.065	-0.060	1.766
G_b14	HDL	0.05	0	-0.141	0.085	0.761
	GLUC	0.15	0	0.340	-0.416	-0.567
	TG	0.2	0	0.390	-0.461	-0.745
G_b15	HDL	0.02	0	-0.156	-0.006	0.144	-0.081	0.069	0.518
	GLUC	0.2	0	0.736	-0.095	-0.649	0.182	-0.372	-0.511
	TG	0.1	0	0.242	-0.161	-0.565	0.444	0.040	-0.363
G_b16	HDL	0.02	0	-0.180	0.049	0.201	-0.104	-0.027	0.582
	GLUC	0.05	0	0.140	0.004	-0.403	0.412	-0.132	-0.268
	TG	0.02	0	0.213	-0.036	-0.201	-0.118	0.047	0.130
G_b17	HDL	0.01	0	0.066	-0.060	-0.186	0.129	0.003	-0.123
	GLUC	0.05	0	-0.237	-0.183	-0.022	0.032	0.139	0.569
	TG	0.05	0	-0.339	-0.143	-0.025	0.053	0.211	0.446
G_b18	HDL	0.005	0	0.026	-0.012	-0.199	0.063	0.101	-0.086
	GLUC	0.01	0	-0.082	-0.004	0.114	0.036	0.153	0.699
	TG	0.01	0	-0.060	0.001	0.032	-0.029	0.245	0.702
G_b19	HDL	0.005	0	0.045	-0.092	-0.147	0.073	-0.010	-0.037
	GLUC	0.01	0	-0.078	0.088	0.155	-0.045	0.254	0.321
	TG	0.005	0	-0.033	-0.005	0.108	-0.005	0.249	0.390
G_b20	HDL	0.15	0	-0.601	-0.204	0.589	-0.403	0.192	0.391
G_b21	HDL	0.05	0	-0.166	0.279	0.428
G_b22	HDL	0.01	0	-0.142	-0.118	-0.046	-0.094	0.122	0.050
G_b23	TG	0.01	0	-0.044	0.077	0.561
G_b24	TG	0.005	0	-0.018	0.046	0.659
G_b25	TG	0.005	0	-0.221	-0.028	0.049	-0.105	0.010	0.126
G_b26	GLUC	0.1	0	-0.212	0.272	0.175	-0.115	0.369	2.208
G_b27	GLUC	0.05	0	-0.150	0.207	0.741
G_b28	GLUC	0.02	0	-0.237	-0.065	0.108	-0.151	0.022	0.194
G_b29	GLUC	0.01	0	-0.128	0.014	0.156
G_b30	CHOL	0.2	0	-0.611	0.240	0.362	-0.489	0.483	0.605
G_b31	CHOL	0.15	0	-0.825	-0.436	-0.047	-0.630	0.148	0.342
G_b32	CHOL	0.1	0	-0.276	-0.140	0.404	0.268	0.676	2.444
G_b33	CHOL	0.05	0	-0.117	-0.053	0.012	-0.085	0.528	1.496
G_b34	SBP	0.25	0	-0.463	0.309	1.080
G_b35	SBP	0.15	0	-0.353	-0.151	0.655
G_b36	SBP	0.1	0	-0.236	0.406	0.535
G_b37	DBP	0.4	0	-0.376	0.877	2.129
G_b38	DBP	0.1	0	-0.118	0.397	2.456
G_s1	WT	0.5	0	-0.445	0.267	2.405
G_s2	WT	0.4	0	-1.146	-0.652	0.334	-0.159	0.828	2.308
G_s3	TG	0.00408	0.058	0	0.05	0.1	0.02	0.2	0.4
	GLUC	5.36E-05	0.00059	-0.01	-0.002	0.002	0.004	0.01	0.03
G_s4	TG	0.00307	0.0633	0	0.01	0.02	0.1	0.12	0.15
	GLUC	1.58E-05	-0.0003	-0.01	-0.003	-0.002	0	0.002	0.005
G_s5	TG	0.00036	0.0446	0.05	0.025	0	0.075	0.04	0.1
	GLUC	8.77E-07	-7E-05	0	-0.001	-0.004	0.001	-5E-04	0.002
G_s6	TG	0.00119	0.09416	0.1	0.12	0.125	0.02	0.05	0
	GLUC	6.34E-06	0.00045	0	0.002	0.0025	-0.002	-0.001	-0.02
G_s7	CHOL	0.36428	0.385	0	0.25	0.5	0.75	2	4
G_s8	CHOL	0.07582	0.291	0	0.1	0.3	0.25	0.5	1
G_s9	CHOL	0.03208	0.265	0.1	0.2	0.4	0.3	0.7	1
G_s10	SBP	0.12424	0.342	0	0.6	1
	DBP	0.03016	0.138	0	0.2	0.6
G_s11	SBP	0.05859	0.1375	0	0.2	1
	DBP	0.01934	0.10625	0	0.2	0.5
G_s12	SBP	0.01574	0.084	0	0.2	0.5
	DBP	0.06054	0.184	0	0.5	0.6

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