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Table 1 Regions with at least suggestive linkage (p < 0.001) for the most parsimonious model

From: Interaction of gender and body mass index (BMI) reveals evidence of linkage for hypertension in the Framingham Heart Study

Chromosome (Location in cM)

Nearest Marker

Lod Score (p-value)

Model Coefficients

  

Mean BMI

Slope BMI

β

γGENDER

γBMI

γGENDER*BMI

2 (74 cM)

D2S1352

7.1 (8.76 × 10-7)

 

0.000

-0.070

0.035

-0.059

4 (142 cM)

D4S1644

4.7 (0.00017)

 

0.330

0.027

0.062

-0.052

12 (8 cM)

D12S372

4.3 (0.00035)

 

0.030

-0.171

0.012

0.050

15 (128 cM)

D15S642

4.1A(0.00004)

 

0.041

 

-0.041

 

18 (34 cM)

D18S843

4.0 (0.00068)

 

0.229

-0.175

0.069

-0.050

1 (276 cM)

D1S547

 

3.9 (0.00091)

0.087

-0.176

0.621

0.687

2 (186 cM)

D2S1384

 

4.3 (0.00037)

0.000

-0.077

0.151

1.205

4 (194 cM)

D4S2417

 

4.1 (0.00057)

0.000

-0.002

0.571

-1.134

19 (75 cM)

D19S589

 

4.3 (0.00037)

0.018

-0.218

0.504

0.577

20 (74 cM)

D20S481

 

4.0 (0.00072)

0.146

0.066

-0.783

-0.713

22 (48 cM)

D22S445

 

5.7 (0.00001)

0.157

0.311

0.594

1.196

  1. ALOD score for a model that includes BMI only. Otherwise, LOD scores are for the full model.