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Table 1 Summarized results of GENEFINDER analysis

From: Comparison of significance level at the true location using two linkage approaches: LODPAL and GENEFINDER

 

Replicate 1

Replicate 2

Replicate 3

 

Without covariate

With covariate

Without covariate

With covariate

Without covariate

With covariate

Chr

LEA

CIB

LE

CI

LE

CI

LE

CI

LE

CI

LE

CI

1

nC

 

192.4

(181.7, 203.1)

251.7

(237.3, 260.1)

248.5

(237.0, 260.0)

238.6

(221.5, 255.7)

245.1*

(235.4, 254.7)

2

n

 

156

(141.8, 170.1)

227.9

(192.3, 263.6)

285.2

(275.5, 295.0)

216.3

(198.4, 234.1)

224.3*

(215.4, 233.2)

3

n

 

31.1

(18.6, 43.6)

67.9

(52.9, 83.0)

199.5

(188.0, 211.0)

151.1

(115.5, 186.6)

150.2

(140.8, 159.7)

4

176.1

(158.3, 193.9)

196.7**

(191.2, 202.3)

84.5

(65.7, 103.3)

92.7

(77.7, 107.6)

85.2

(76.5, 93.9)

86.4***

(81.7, 91.1)

5

75.2

(46.2, 104.2)

16.2*

(9.3, 23.2)

83.6

(50.4, 116.8)

85

(72.7, 97.3)

n

 

56.4

(49.3, 63.6)

6

46.2**

(40.9, 51.5)

53.0*

(48.3, 57.6)

94.1*

(80.9, 107.2)

90.2***

(80.9, 99.5)

52.9

(42.4, 63.4)

50.7

(40.4, 61.1)

7

n

 

110.2

(94.3, 126.0)

69.2*

(59.7, 78.6)

79.5*

(72.6, 86.3)

n

 

83.47

(71.6, 95.4)

8

n

 

142.2

(133.0, 51.3)

114.5

(92.1, 137.0)

114.4

(97.5, 131.3)

2

(0, 120.0)

54.65

(40.4, 68.9)

9

26.3

(14.4, 38.2)

24.7

(10.1, 39.2)

138.4*

(128.1, 148.6)

138.1*

(128.1. 148.0)

16.6

(2.5, 30.7)

22

(9.8, 34.3)

10

187.9

(175.4, 200.4)

151.4*

(144.3, 158.6)

47.9

(35.9, 59.8)

49.2

(38.7, 59.7)

n

 

173.9*

(165.0, 182.9)

11

5.8

(0, 38.5)

38.1

(28.3, 48.0)

53.4

(33.3, 73.6)

57.5

(47.0, 68.0)

n

 

52.7*

(44.7, 60.7)

12

146.4

(120.0, 172.8)

72

(62.5, 81.5)

n

 

69.7***

(63.35, 76.1)

79.4

(60.9, 97.8)

33.7*

(24.0, 43.3)

13

63.1

(16.2, 100.0)

94.4

(84.2, 104.6)

87.5

(72.8, 102.2)

67

(58.1, 76.0)

n

 

112.3

(99.1, 125.5)

14

118.2

(72.9, 163.6)

107.4***

(103.4, 111.4)

n

 

79.4

(57.2, 101.7)

n

 

106.9

(91.5, 122.3)

15

123

(105.0, 140.9)

112.1

(107.1, 117.2)

n

 

82.8*

(74.0, 91.6)

92.8

(54.7, 130.8)

104.3

(94.0, 114.5)

16

46.7

(27.1, 66.2)

48.1

(34.5, 61.7)

92.8

(63.1, 122.5)

120.1*

(110.9, 129.2)

124.1

(0, 297.3)

116.7

(98.6, 134.8)

17

137.5

(115.2, 159.8)

134.5

(122.1, 146.9)

118.6

(97.9, 139.2)

80.4

(62.8, 97.9)

n

 

57.6*

(51.1, 64.1)

18

n

 

23.2

(11.5, 34.8)

25.1

(3.3, 46.8)

24.3

(3.5, 45.0)

n

 

11.5**

(5.7, 17.3)

19

n

 

72.0**

(59.4, 84.7)

14.8

(0.1, 29.4)

29

(14.7, 43.2)

–D

 

68.4***

(63.2, 73.7)

20

56.5

(36.8, 76.3)

88.1

(80.5, 95.7)

n

 

95.7

(73.3, 118.0)

36.2

(20.0, 52.3)

39.7*

(32.0, 47.4)

21

–

 

47.9

(27.6, 68.2)

n

 

38.9

(23.5, 54.3)

n

 

42.1*

(37.1, 47.2)

22

–

 

40

(25.9, 54.1)

17.7

(0, 66.5)

37.6**

(33.2, 42.1)

38.9

(12.5, 65.3)

9.9

(0, 25.4)

  1. ALE, location estimate. BCI, 95% confidence interval. Cn, converge to the minimum not the maximum. D_, not convergent. *p-value < 0.05; **p-value < 0.005; ***p-value < 0.0005