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Table 2 Results from bivariate linkage analyses of the trait pair ln BMI-ln HDL-C phenotypes

From: Evidence for bivariate linkage of obesity and HDL-C levels in the Framingham Heart Study

Trait Pair

cMA

ρqB

Bivariate LOD

λC

P D

LODeqE

ln BMI-ln HDL

152

-0.54

6.24

28.75

1.8 × 10-7

5.46

  1. ADistance from pter; Bρq is correlation due to QTL effects; Clikelihood-ratio statistic λ. DAsymptotic P value, under the assumption that λ is distributed as a 1/4X22 : 1/2X21 : 1/4X20 mixture. ELodeq is the univariate lod score corresponding to the reported bivariate lod score