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Table 1 Cross-sectional analyses: heritabilities and covariate effects for three traits within age-classes from univariate quantitative genetic analyses of data from Framingham Heart Study subjects measured in the 4th and 6th decades of life.

From: Pleiotropic effects on cardiovascular risk factors within and between the fourth and sixth decades of life: Implications for genotype × age interactions

    

p-Values of Covariates Screened

Trait

h2

c2A

n

Sex

Age

CPD

HRx

Wgt

30-39 Years

        

   Total Cholesterol

0.34

0.06

984

<0.001

 

<0.001

 

-B

   Systolic Blood Pressure

0.10

0.15

994

<0.01

 

<0.05

 

<0.001

   Body Weight

0.48

0.49

1239

<0.001

<0.01

 

<0.001

-

50-59 Years

        

   Total Cholesterol

0.29

0.02

818

<0.001

  

<0.10

-

   Systolic Blood Pressure

0.32

0.04

968

 

<0.001

 

<0.05

<0.001

   Body Weight

0.45

0.26

881

<0.001

 

<0.001

<0.001

-

  1. Ac2, proportion of phenotypic variance due to covariates. B-, not screened.