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Table 2 Genome Screen Results for Single Exam (SE)

From: Identification of genes for complex disease using longitudinal phenotypes

Phenotype

h2

n

covarA

1

3

5

7

9

11

13

15

17

19

21

false+

BMI

SE

75.3

2585

a,g

0.6

0.9

1.4

0.9

0.7

1.0

22.6

1.0

1.6

0.1

0.0

1.7

 

AUCB

76.0

2585

a,g

0.6

0.5

1.6

1.2

0.9

1.0

23.9

0.9

1.4

0.2

0.0

1.4

Chol

SE

58.6

2550

a,g

0.9

0.8

0.7

1.3

0.8

5.7

0.7

2.2

0.4

0.8

0.9

1.4

 

AUC

67.7

2550

a,d,g

1.7

0.5

0.1

1.0

2.1

5.6

1.1

3.1

0.4

0.4

1.9

1.5

Gluc

SE

50.8

2558

a

3.1

1.5

20.7

0.5

0.6

1.3

1.3

0.4

0.1

0.7

0.2

4.7

 

AUC

67.1

2558

a

1.8

1.1

48.8

0.9

0.2

3.0

1.1

0.0

0.3

3.2

0.0

3.9

HDL

SE

63.8

2565

a,b,c,d,g

1.8

0.5

0.5

1.2

8.9

0.5

0.8

0.1

5.5

1.0

0.5

2.5

 

AUC

65.3

2565

a,c,d,g

1.9

0.9

0.7

0.9

9.3

0.7

0.6

0.2

6.9

1.3

0.8

2.7

Height

SE

73.7

2585

g

0.2

1.1

12.3

4.7

0.3

0.2

1.9

0.6

0.3

0.2

0.0

0.7

 

AUC

75.0

2585

g

0.4

0.8

13.8

5.1

0.5

0.2

1.3

1.0

0.6

0.1

0.0

0.9

SBP

SE

57.1

2585

a,b,c

0.1

1.2

2.7

2.8

0.8

0.1

2.9

3.2

1.2

1.3

19.3

2.5

 

AUC

75.1

2585

a,b,c

0.1

1.7

1.9

2.1

0.5

0.0

1.3

6.3

0.4

1.0

30.6

2.2

Tg

SE

41.4

2526

a,b,d,g

4.2

0.9

1.5

0.8

2.8

0.5

0.8

0.8

3.7

1.4

0.4

4.5

 

AUC

47.2

2526

a,b,d,g

3.9

0.2

3.6

1.0

0.9

0.9

1.2

0.6

1.1

2.0

0.1

1.5

  1. ASignificant covariates employed in the linkage analysis (a, average age in study; b, body mass index; c, cigarettes per day; d, drinks, alcohol consumption; g, gender). BResults of the longitudinal data with only those individuals included in the cross-sectional design. Only odd chromosomes contain genes; even chromosomes are summarized as highest false positive (false+).