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Table 3 Genome Screen Results for AGE = 45

From: Identification of genes for complex disease using longitudinal phenotypes

Phenotype

h2

n

covar.A

1

3

5

7

9

11

13

15

17

19

21

false+

BMI

AGE = 45

76.0

2674

g

0.3

0.1

1.1

0.6

1.2

1.3

20.2

0.5

1.0

0.2

0.1

1.5

 

AUCB

76.2

2674

g

0.5

0.2

1.6

1.0

1.1

1.0

23.0

1.3

1.2

0.3

0.0

1.7

Chol

AGE = 45

59.7

2650

g

1.6

0.4

0.1

1.0

1.2

3.4

0.9

3.2

0.4

0.3

1.7

1.2

 

AUC

66.6

2650

a,g

1.3

0.7

0.1

0.5

0.7

4.9

0.6

3.4

0.2

0.3

1.4

1.2

Gluc

AGE = 45

64.6

2412

-

1.0

0.9

22.2

0.3

1.9

0.5

0.0

0.1

0.4

0.1

0.1

1.3

 

AUC

62.9

2412

a

1.3

1.0

25.1

0.3

1.7

1.2

0.0

0.0

0.9

0.3

0.0

3.1

HDL

AGE = 45

65.4

1600

b,c,d,g

2.2

0.5

0.1

1.3

8.5

0.4

0.9

0.0

9.8

0.5

0.6

2.4

 

AUC

66.1

1600

b,c,d,g

2.9

0.8

0.5

1.1

9.0

0.2

0.5

0.0

8.6

0.7

0.3

2.8

Height

AGE = 45

73.7

2585

g

0.2

1.1

12.3

4.7

0.3

0.2

1.9

0.6

0.3

0.2

0.0

0.7

 

AUC

75.0

2585

g

0.4

0.8

13.8

5.1

0.5

0.2

1.3

1.0

0.6

0.1

0.0

0.9

SBP

AGE = 45

74.7

2411

a,b,c

0.5

0.8

2.0

1.5

1.1

0.1

1.2

3.6

0.3

1.2

21.1

2.1

 

AUC

71.3

2411

a,b,c

0.7

2.4

2.7

3.0

0.7

0.0

1.4

5.3

0.3

0.8

26.8

1.9

Tg

AGE = 45

53.2

1585

a,b,d,g

6.2

0.2

0.9

0.7

1.7

1.4

0.3

0.3

0.6

0.3

0.5

1.6

 

AUC

51.9

1585

a,b,d,g

7.6

0.2

0.7

1.3

2.9

2.5

0.3

0.2

0.6

0.5

0.4

1.1

  1. ASignificant covariates employed in the linkage analysis (a, average age in study; b, body mass index; c, cigarettes per day; d, drinks, alcohol consumption, g, gender). BResults of the longitudinal data with only those individuals included in the cross-sectional design. Only odd chromosomes contain genes; even chromosomes are summarized as highest false positive (false+).