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Table 2 Bayesian approach result for Replicate 54

From: Linkage analysis of the simulated data – evaluations and comparisons of methods

  Model Marginalc Joint
No. Freq.a Penetrancesb 1 1 2 2
1 0.2 0.05 0.50 0.70 1.00 42.2 0.92 38.5 0.92 46.3
2 0.1 0.10 0.50 0.70 1.00 42.3 0.85 37.8 0.90 46.4
3 0.2 0.00 0.20 0.50 1.00 42.4 0.89 39.2 0.92 48.3
4 0.2 0.00 0.50 0.60 1.00 41.7 0.85 36.9 0.92 45.4
5 0.2 0.00 0.35 0.55 1.00 41.8 0.81 38.2 0.92 46.3
6 0.3 0.00 0.60 1.00 1.00 42.9 0.51 30.7 0.98 45.6
7 0.3 0.00 0.20 0.60 1.00 42.6 0.96 39.7 0.93 48.6
8 0.3 0.00 0.40 0.80 1.00 42.4 0.95 39.2 0.95 48.2
  1. aFreq., P(D), where D is disease allele. bPenetrances are for genotypes dd, Dd, DD, in that order. c and represent the estimated posterior probability of linkage and the corresponding position of the disease gene for the marginal analysis. Similar notations for joint analysis are used.