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Table 4 Effect of MI on linkage results on chromosome 21 with different amounts of missing data

From: Genome-wide linkage analysis of systolic blood pressure slope using the Genetic Analysis Workshop 13 data sets

  

Max LOD Score

%A

# of Missing Values per Subject

Two-PointB

Multipoint

  

Without MI

With MI

Without MI

With MI

0

0

9.66 C

 

13.45 (52 cM) C

 

10

1

9.39

9.82

13.30 (52 cM)

13.32 (52 cM)

 

2 or more

11.08

10.20

14.69 (51 cM)

13.51 (51 cM)

25

1

9.38

9.66

13.11 (52 cM)

13.30 (51 cM)

 

2 or more

7.41

8.63

9.16 (49 cM)

11.67 (50 cM)

  1. APercentage of subjects with missing data. BTwo-point LOD scores were found at the same location. CReference values.