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Table 2 Regions with at least suggestive evidence under one analysis.A

From: Comparison of linkage analysis methods for genome-wide scanning of extended pedigrees, with application to the TG/HDL-C ratio in the Framingham Heart Study

Chr

cM

Nearest Marker

LINKAGE

GH

MCLINKB

SOLARC

1

276

203yg9

-D

-

1.93 (276 cM, HD)

-

2

201–05

GATA65C03

1.26 (205 cM, lr)

-

2.29 (201 cM, lr)

-

3

135–41

GATA84B12

-

-

1.74 (135 cM, HD)

1.89 (m;141 cM)

      

2.50 (2;135 cM)

3

194

GATA3H01

1.95 (195 cM, Hr)

-

1.98 (194 cM, Hr)

-

5

103

GATA69H12

-

2.34 (103 cM, HD)

1.51 (103 cM, HD)

-

5

125

ATA4D10

1.45 (125 cM, HD)

2.65 (125 cM, HD)

1.57 (125 cM, HD)

-

7

48–57

GATA13G11

-

1.97 (52 cM, HD)

-

-

7

161–69

GATA32C12

-

1.52 (161 cM, Hr)

1.17 (156 cM, HD)

2.12 (m;169 cM)

      

2.67 (2;163 cM)

8

176

UT721

-

2.26 (176 cM, lr)

-

-

10

32–33

ATA31G11

1.82 (32 cM, lD)

-

1.94 (33 cM, lr)

-

13

36

GATA86H01

2.12 (36 cM, lD)

-

-

-

17

126–29

044xg3

1.12 (128 cM, lr)

2.10 (129 cM, lr)

1.44 (126 cM, lr)

1.13 (2;127 cM)

19

0–11

GATA44F10

1.63 (11 cM, lD)

2.07 (0 cM, lD)

1.61 (0 cM, lD)

-

22

21

Mfd313

3.37 (21 cM, lr)

-

-

1.28 (2; 21 cM)

  1. AA region is reported only when at least one analysis produced a score over 1.9. In those regions all other analyses that reached at least a score >1.0 are also reported. BH, loci linked to high TG/HDL ratio; l, low TG/HDL-C ratio; D, dominant model; r, recessive model. CBoth two- and multi-point variance component analyses were performed in SOLAR (2 indicates two-point, m indicates multipoint results). DIndicates no score above 1.0.