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Table 4 List of genes grouped under gene ontology molecular functions that showed changes in the discordant monozygotic (MZ) twin pairs but not the concordant pair.

From: Variations in genome-wide gene expression in identical twins – a study of primary osteoblast-like culture from female twins discordant for osteoporosis

Probe Set ID

Gene Name

Fold changed

Gene Symbol

5125 Cytokine activity in 2A/2B decrease

204926_at

inhibin, beta A (activin A, activin AB alpha polypeptide)

2.1

INHBA

205067_at

interleukin 1, beta

4.3

IL1B

205476_at*

chemokine (C-C motif) ligand 20

3.0

CCL20

205767_at

Epiregulin

3.3

EREG

206569_at

interleukin 24

3.3

IL24

210557_x_at

colony stimulating factor 1 (macrophage)

2.1

CSF1

211839_s_at

colony stimulating factor 1 (macrophage)

2.8

CSF1

221577_x_at*

prostate differentiation factor

2.3

PLAB

39402_at

interleukin 1, beta

4.0

IL1B

8083 Growth factor activity in 2A/2B decrease

204926_at

inhibin, beta A (activin A, activin AB alpha polypeptide)

2.1

INHBA

205067_at

interleukin 1, beta

4.3

IL1B

205767_at

Epiregulin

3.3

EREG

210557_x_at

colony stimulating factor 1 (macrophage)

2.1

CSF1

211839_s_at

colony stimulating factor 1 (macrophage)

2.8

CSF1

221577_x_at*

prostate differentiation factor

2.3

PLAB

39402_at

interleukin 1, beta

4.0

IL1B

5194 Cell adhesion molecular activity in 2A/2B increase

202877_s_at

complement component 1, q subcomponent, receptor 1

2.0

C1QR1

203477_at

collagen, type XV, alpha 1

2.0

COL15A1

204677_at**

cadherin 5, type 2, VE-cadherin (vascular epithelium)

5.7

CDH5

208983_s_at**

platelet/endothelial cell adhesion molecule (CD31 antigen)

3.5

PECAM1

212713_at

microfibrillar-associated protein 4

3.7

MFAP4

3700 Transcription factor activity in 3A/3B decrease

207034_s_at

GLI-Kruppel family member GLI2

2.0

GLI2

207147_at

distal-less homeo box 2

2.6

DLX2

208003_s_at

nuclear factor of activated T-cells 5, tonicity-responsive

3.3

NFAT5

208859_s_at

alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)

2.8

ATRX

209088_s_at

ubinuclein 1

2.1

UBN1

212420_at

E74-like factor 1 (ets domain transcription factor)

2.1

ELF1

215698_at

retinoblastoma binding protein 2

2.1

RBBP2

3700 Transcription factor activity in 3A/3B increase

205991_s_at

paired mesoderm homeo box 1

2.0

PMX1

207001_x_at

delta sleep inducing peptide, immunoreactor

2.0

DSIPI

207558_s_at

paired-like homeodomain transcription factor 2

3.7

PITX2

208502_s_at

paired-like homeodomain transcription factor 1

8.6

PITX1

210135_s_at

short stature homeobox 2

7.5

SHOX2

221950_at

empty spiracles homolog 2 (Drosophila)

4.3

EMX2

5194 Cell adhesion activity in 3A/3B increase

204677_at

cadherin 5, type 2, VE-cadherin (vascular epithelium)

3.5

CDH5

208983_s_at

platelet/endothelial cell adhesion molecule (CD31 antigen)

2.6

PECAM1

  1. * Also show decrease in 1A/1B pair but the changes were less than 2 folds ** Also show increase in 3A/3B pair