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Table 1 HLA DR phenotypic frequencies according to p-values and Odds ratio in type 1 diabetic and nondiabetic subjects.

From: HLA DR phenotypic frequencies and genetic risk of Type 1 diabetes in west region of Algeria, Tlemcen

 

Type 1 diabetics n = 39: 15 M/24 F

Nondiabetic controls n = 52: 21 M/31F

  
 

Frequency (Proportion and %)

  

HLA

M

F

M

F

p

Odds ratio (95 % CI)

DR3

3 (7.69)

7 (17.9)

5 (9.62)

9 (17.31)

0.2646a

0.95 (0.48–1.87)

 

10 (25.64)

14 (26.92)

1.000

 

DR4

4 (10.26)

9 (23.08)

6 (11.54)

4 (7.69)

0.0085 a, *

2.10 (1.04–4.24)

 

13 (33.33)

10 (19.23)

0.0361*

 

DR3DR4

4 (10.26)

4 (10.26)

2 (3.85)

7 (13.46)

0.0699a

1.30 (0.60–2.80)

 

8 (20.51)

9 (17.31)

0.5887

 

DR3 and/or DR4

11 (28.21)

20 (51.28)

13 (25.0)

20 (38.46)

0.5791a

2.21 (1.13–4.36)

 

31 (79.49)

33 (63.46)

0.0194*

 

X/X

4 (10.26)

4 (10.26)

8 (15.38)

11 (21.15)

0.0111 a, *

-

 

8 (20.51)

19 (36.54)

0.0194*

 
  1. ap-Values related to the sex ratio comparison (male = M, female = F). * p < 0.05. X = non-DR3, non-DR4.