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Table 6 Comparison of SNP allele frequencies of the studied Caucasian sample with the data on Hispanics from databases and literature

From: Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis

Gene SNP Database or references Data from a database or reference Caucasiansa P
    Frequencyb n Frequency n  
ER-α 12 dbSNP 0.239 23 0.218 1,859 1.00
  15 dbSNP 0.196 23 0.203 1,863 1.00
IL-6 16 dbSNP 0.795 22 0.434 1,860 <0.01
TGF-ß1 26 dbSNP 0.413 23 0.311 1,840 0.36
UCP3 33 [73] 0.00 27 0.000 295 1.00
  36 [73] 0.02 27 0.000 295 1.00
VDR 41 dbSNP 0.348 23 0.408 1,859 0.83
  1. For gene abbreviations and SNP designations see Table 1. aPresent study. bFrequency of the allele corresponding to a minor allele in the present study.