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Table 7 Comparison of SNP allele frequencies of the studied Caucasian sample with the data on Pacific Rim populations from databases

From: Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis

Gene SNP Database Data from a database or reference Caucasiansa P
    Frequencyb n Frequency n  
ER-α 12 dbSNP 0.478 23 0.218 1,859 0.02
  15 dbSNP 0.326 23 0.203 1,863 0.19
IL-6 16 dbSNP 0.957 23 0.434 1,860 <0.01
TGF-ß1 26 dbSNP 0.458 24 0.311 1,840 0.19
VDR 41 dbSNP 0.13 23 0.408 1,859 <0.01
  1. For gene abbreviations and SNP designations see Table 1. aPresent study. bFrequency of the allele corresponding to a minor allele in the present study