Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis

Table 7 Comparison of SNP allele frequencies of the studied Caucasian sample with the data on Pacific Rim populations from databases

Gene	SNP	Database	Data from a database or reference		Caucasians^a		P
			Frequency^b	n	Frequency	n
ER-α	12	dbSNP	0.478	23	0.218	1,859	0.02
	15	dbSNP	0.326	23	0.203	1,863	0.19
IL-6	16	dbSNP	0.957	23	0.434	1,860	<0.01
TGF-ß1	26	dbSNP	0.458	24	0.311	1,840	0.19
VDR	41	dbSNP	0.13	23	0.408	1,859	<0.01

For gene abbreviations and SNP designations see Table 1. ^aPresent study. ^bFrequency of the allele corresponding to a minor allele in the present study

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