Searching QTL by gene expression: analysis of diabesity

BMC Genomic Data

Table 2 GPR report of B6 vs. TH gene expression comparisons.¹

Gene	# Total hits²	GPR Score³	Fold change⁴
	Adipose
Pparg	44	0.92	-14.9
Lep	40	0.83	5.3
Alb1	39	0.81	-9.4
Gsta3	38	0.79	-10.6
Glut2	37	0.77	-28.1
Fmo1	35	0.73	-4.8
Scp2	25	0.52	-2.4
Agpat2	24	0.50	-2.9
Agpat3	19	0.40	-2.1
	Pancreas
Ela2	39	0.95	-55.8
Pnliprp2	39	0.95	-21.8
Kitl	29	0.71	-4.3
Col18a1	18	0.44	-1.7
Ela3b	16	0.40	-1.8
	Liver
Tff3	63	1.00	-593.0
Vldlr	58	0.92	15.6
Hsd17b9	57	0.91	9.5
Pparg	56	0.89	-11.5
Igfbp2	46	0.73	-2.7
Kitl	39	0.62	-2.4
Decr2	28	0.44	-1.3
Lpl	25	0.40	-1.2
Pi4k2a	25	0.40	-1.1

¹ Complete GPR report and raw CT data in Supplementary Data.
²Number of qualified normalizer genes against which test gene ΔC_T values are statistically significant at p = 0.05.
³ # of total hits / # of qualified normalizers. A GPR score = 0.40, meaning that the test gene ΔC_T comparisons differed at p= 0.05 compared with at least 40% of the qualified normalizers, is considered most reliable.
⁴Relative to 18S RNA.

ISSN: 2730-6844