Table 3 Medline citations to genes showing altered expression in TH mice.
From: Searching QTL by gene expression: analysis of diabesity
Gene name | Diabesity-relevant articles | General function |
|---|---|---|
Genes chosen known to be involved in diabetes with expression change | ||
Alb1 | 5548 | Lipid binding and carrier activity |
Leptin | 3170 | Hormone activity |
Lpl | 775 | Lipid catabolism or fatty acid metabolism |
Pparg | 702 | Lipid metabolism and steroid hormone receptor activity |
Glut2 | 142 | Glucose transport and carbohydrate metabolism |
Agpat2 | 5 | Phospholipid biosynthesis |
ExQuest chosen genes with expression change, known or unknown to be involved in diabetes | ||
Col18a1 1 | 7 | Potent antiangiogenic protein, structural molecule |
Vldlr 2 | 7 | Lipid transport |
Scp2 | 4 | Sterol carrier activity, lipid binding, and steroid biosynthesis |
Fmo1 | 3 | Electron transport and oxidoreductase activity |
Pnliprp2 | 1 | Lipid catabolism |
KitL | 0 | Signal transduction |
Igfbp2 | 0 | Insulin-like growth factor binding |
Ela2 | 0 | Proteolysis and peptidolysis |
Ela3b | 0 | Proteolysis and peptidolysis, and cholesterol metabolism |
Gsta3 | 0 | Biosynthesis of steroid hormones |
Agpat3 | 0 | Phospholipid metabolism |
Hsd17b9 | 0 | Steriod biosynthesis and oxidoreductase activity |
Decr2 | 0 | Peroxisome organization and biogenesis, and oxidoreductase activity |
Tff3 | 0 | Epithelium healing |
Pi4k2a | 0 | Inositol/phosphatidlinositol kinase activity |
Functional summary of genes with expression changes 3 | ||
Lipid related gene activity | 8 | |
Hormone related gene activity | 6 | |
Inflammation or response to injury | 4 | |
Oxidoreductase activity | 3 | |
Signal transduction | 3 | |
Proteolysis and peptidolysis | 2 | |
Carbohydrate related gene activity | 1 | |