Table 1 Transmission disequilibrium of 13 VDR-SNPs in affected and unaffected children. P-values < 0.05 are indicated in bold.
asthma | no asthma | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LD block * | dbSNP | allele | chr12 (bp) | geno-types | freq (%) | T | UT | T/UT | P | T | UT | T/UT | P | P TDTDS |
A | hCV2880804 | C | 47954855 | 918 | 28 | 170 | 178 | 1,0 | 0,668 | 18 | 33 | 0,5 | 0,049 | 0,055 |
-- | rs2228570 | T | 47977944 | 724 | 35 | 159 | 150 | 1,1 | 0,609 | 21 | 12 | 1,8 | 0,117 | 0,079 |
? | rs3819545 | C | 47981753 | 912 | 38 | 186 | 191 | 1,0 | 0,797 | 25 | 31 | 0,8 | 0,423 | 1,000 |
B | rs3782905 | G | 47982914 | 934 | 32 | 201 | 174 | 1,2 | 0,163 | 26 | 27 | 1,0 | 0,891 | 0,388 |
? | rs2853563 | G | 48248398 | 661 | 97 | 20 | 24 | 0,8 | 0,547 | -- | -- | -- | -- | -- |
B | rs731236 | C | 48251417 | 923 | 37 | 202 | 206 | 1,0 | 0,843 | 25 | 29 | 0,9 | 0,586 | 0,767 |
B | rs1544410 | A | 48252495 | 896 | 37 | 190 | 186 | 1,0 | 0,837 | 23 | 26 | 0,9 | 0,668 | 1,000 |
B? | rs2239185 | C | 48257219 | 903 | 49 | 198 | 214 | 0,9 | 0,431 | 29 | 24 | 1,2 | 0,492 | 0,650 |
? | rs987849 | C | 48267336 | 825 | 45 | 164 | 169 | 1,0 | 0,784 | 28 | 18 | 1,6 | 0,140 | 0,173 |
B | rs1540339 | A | 48269986 | 916 | 36 | 189 | 187 | 1,0 | 0,575 | 25 | 27 | 0,9 | 0,782 | 0,706 |
? | rs2239186 | C | 48282070 | 929 | 19 | 116 | 145 | 0,8 | 0,073 | 20 | 18 | 1,1 | 0,746 | 0,189 |
C | rs1989969 | T | 48290670 | 922 | 43 | 204 | 198 | 1,0 | 0,765 | 39 | 20 | 2,0 | 0,013 | 0,025 |
C | rs2853564 | C | 48291147 | 920 | 44 | 196 | 201 | 1,0 | 0,802 | 38 | 20 | 1,9 | 0,018 | 0,021 |