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Table 1 Birth size and cord IGF-II levels by offspring H19 2992 genotype (ALSPAC cohort)

From: Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans

 

CC

CT

TT

PA

PD

 

(n = 1075)

(n = 518)

(n = 54)

  

Weight (gm)

3468 ± 488

3522 ± 486

3524 ± 587

0.03

0.02

Length (cm)

50.7 ± 2.0

50.9 ± 2.0

50.9 ± 2.1

0.08

0.06

Head circ. (cm)

34.9 ± 1.2

34.9 ± 1.3

35.0 ± 1.6

0.3

0.4

 

(n = 226)

(n = 110)

(n = 13)

  

Cord IGF-II (ng/dl)

275 ± 78

277 ± 79

337 ± 91

0.1

0.3

  1. Mean ± SD, adjusted for sex, gestation and parity.
  2. PA = P value for additive genetic model (per T allele)
  3. PD = P value for dominant genetic model (CC versus T/*)