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Table 5 Index of similarity (I F ) between haplotype frequencies estimated with and without molecular haplotyping information.

From: Inferring haplotypes at the NAT2 locus: the computational approach

 

PL-EM

PHASE

258 Spanish [45]

0.996

0.996

137 Nicaraguans [30]

0.986

0.986

112 UK Caucasians [24]

0.994

0.998

101 Black South Africans [24]

0.981

0.988

1000 Koreans [31]

0.997

0.998

  1. Computations of I F indices were based on the haplotype frequency estimates obtained by considering all possible haplotype configurations (with a nonzero probability) inferred for each subject, weighted by their estimated probability. Note that such estimates can be rather different from those obtained by gene counting on the basis of the "best" reconstruction (that is, when only the most probable pair of haplotype is selected for each sampled individual). Since Haplotyper only provides a summary of the frequency with which each haplotype occurred in the "best" reconstruction, it was excluded from the comparison.
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BMC Genomic Data

ISSN: 2730-6844

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