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Figure 3 | BMC Genetics

Figure 3

From: The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension

Figure 3

Plasma sterols as a function of Abcg5 genotypes. Cholesterol (panel A) and sitosterol (panel B) were segregated in all F2 animals by Abcg5 Gly583Cys. While there were no differences between cholesterol values between any of the genotypes, F2 rats who were homozygous for Cys583 (HMZ) showed significantly higher plasma sitosterol values (*, P < 0.05, mean 5.12 ± 0.25 mg/dl) compared to either heterozygous animals (HET, mean 2.68 ± 0.16 mg/dl) or wild-type (WT, mean 2.25 ± 0.20 mg/dl). These data were analyzed with the inclusion of two 'outliers' (arrows), one in the WT group and one in the HMZ group, where re-analyses to confirm these values were not possible (see Text).

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BMC Genomic Data

ISSN: 2730-6844

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