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Figure 1 | BMC Genetics

Figure 1

From: Assessing the power of tag SNPs in the mapping of quantitative trait loci (QTL) with extremal and random samples

Figure 1

The power using SNPs with a random sampling scheme for different population models. The power is obtained using single-SNP and two-locus haplotype data based on 1,000 simulations with a moderate QTL. In each bin, the figure shows the power based on marker-by-marker analysis and two-locus haplotype analysis (from left to right). Between bins, it shows the power using (from left to right): (1) all SNPs; (2) the tag SNPs identified using the haplotype diversity [4]; (3) the tag SNPs identified using r2 [6]; (4) the evenly spaced SNPs with minor allele frequencies greater than 0.05; (5) the evenly spaced SNPs with minor allele frequencies greater than 0.10; (6) the evenly spaced SNPs with minor allele frequencies greater than 0.15; (7) the evenly spaced SNPs with minor allele frequencies greater than 0.05; and (8) the randomly selected SNPs. In each graph, the method having the highest power based on two-locus haplotype analysis is indicated with the "+" sign. The methods having power significantly lower than the highest one (one-sided chi-square test with 0.05 type I error rate) are indicated with the "*" sign.

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