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Figure 1 | BMC Genetics

Figure 1

From: The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density

Figure 1

Summary of DAT1 constructs used in Flp-In recombination protocol. Top left: hDAT, DAT1 coding region necessary and sufficient to produce a functional transporter protein. Top right: hDAT Zero, a construct containing the DAT1 coding region flanked by an ~800 bp fragment of the 3'UTR upstream of the VNTR region. Bottom left: hDAT 9, a construct with the DAT1 coding region upstream of a full length 3'UTR harboring the 9-repeat VNTR. Bottom right: hDAT 10, a construct with the DAT1 coding region upstream of a full length 3'UTR containing the 10-repeat VNTR.

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