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Table 4 Disease association results. Multi-locus test P values, lengths of re-sequenced genomic regions, and number of tag SNPs or single SNPs genotyped in a two-step genotyping design for NRAMP1, 4-1BB, FRAP1, CD101, B2M, and VAV3.

From: Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes

Locus

Multilocus test P value/ Single-locus TDT P value

Case-control

Combined test P value

 

Family set 1

Family set 1 + 2

  

NRAMP1

-

0.56

0.20

0.68

4-1BB

0.71

-

-

-

 

0.88

-

-

-

 

0.52

-

-

-

 

0.35

-

-

-

 

0.53

-

-

-

 

0.29

-

-

-

 

0.95

-

-

-

 

0.24

-

-

-

FRAP1

0.44

-

-

-

CD101

0.68

-

-

-

B2M

0.90

-

0.11

0.75

VAV3

0.26 (block 1)

-

-

-

 

0.80 (block 2)

-

-

-

 

0.86 (block 3)

-

-

-