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Table 1 Results of association tests for multi-allelic markers

From: Methods to test for association between a disease and a multi-allelic marker applied to a candidate region

Marker

Number of alleles

Allele count (frequency)

Score U*

Terwilliger's LR

Pearson's χ2*

  

Cases

Controls

   

D03S0124

 

5

09 (0.045)

06 (0.060)

0.910

0.500

0.930

  

31 (0.155)

16 (0.160)

   
  

28 (0.140)

11 (0.110)

   
  

75 (0.375)

39 (0.390)

   
  

57 (0.275)

28 (0.280)

   

D03S0125

 

4

12 (0.060)

03 (0.030)

0.069

0.070

0.053

  

79 (0.395)

27 (0.270)

   
  

55 (0.275)

31 (0.310)

   
  

54 (0.270)

39 (0.390)

   

D03S0126

 

7

22 (0.110)

16 (0.160)

0.426

0.500

0.428

  

08 (0.040)

05 (0.050)

   
  

64 (0.320)

37 (0.370)

   
  

16 (0.080)

10 (0.10)

   
  

23 (0.115)

06 (0.060)

   
  

51 (0.255)

18 (0.180)

   
  

16 (0.080)

08 (0.080)

   

D03S0127

 

8

12 (0.060)

03 (0.030)

0.008

0.033

0.007

  

33 (0.165)

20 (0.200)

   
  

33 (0.165)

05 (0.050)

   
  

23 (0.115)

13 (0.130)

   
  

08 (0.040)

04 (0.040)

   
  

14 (0.070)

20 (0.200)

   
  

39 (0.195)

16 (0.160)

   
  

38 (0.190)

19 (0.190)

   
  1. *p-Values were obtained using 10000 Monte-Carlo simulations