Table 2 Estimated FWER of Bonferroni and Storey's FDR approaches. Estimated FWER when none of the SNPs associated with the phenotype (m0 = m) and when some of the SNPs associated with the phenotype (m0 <m) based on the 100 simulated datasets.
From: Power and type I error rate of false discovery rate approaches in genome-wide association studies
α | FWER (m0 = m)a | FWER (m0 <m) | ||
|---|---|---|---|---|
| Â | Bonferroni | Storey's FDR | Bonferroni | Storey's FDR |
0.01 | 0 | 0 | 0.03 | 0.03 |
0.05 | 0.01 | 0.01 | 0.08 | 0.21 |
0.10 | 0.03 | 0.03 | 0.15 | 0.37 |
0.15 | 0.06 | 0.06 | 0.21 | 0.46 |