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Table 2 Empirical significance levels and 95% confidence intervals for original TDT and TDTae

From: Precision and type I error rate in the presence of genotype errors and missing parental data: a comparison between the original transmission disequilibrium test (TDT) and TDTae statistics

Significance level

TDT (95% CI)

TDTae (95% CI)

5%

0.288 (0.279–0.297)

0.052 (0.047–0.057)

1%

0.148 (0.141–0.155)

0.012 (0.009–0.014)

0.1%

0.054 (0.049–0.059)

5.1 × 10-4 (1.4 × 10-4-1.3 × 10-3)

0.01%

0.017 (0.015–0.020)

1.3 × 10-4 (3.3 × 10-6-7.2 × 10-4)

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BMC Genomic Data

ISSN: 2730-6844

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