Calculation of multipoint likelihoods using flanking marker data: a simulation study

BMC Genomic Data

Table 1 Comparison of CHROM-WALK and GENEHUNTER HLOD scores for different marker sets

Chr	Chr 1 Pos	Mset4		Mset16		MsetAll
		HLOD_FL	HLOD_GH	HLOD_FL	HLOD_GH	HLOD_FL	HLOD_GH
1	175 cM	1.96 (0.15)	2.23 (0.15)	1.95 (0.15)	2.30 (0.16)	1.94 (0.15)	2.30 (0.16)
3	312 cM	1.57 (0.14)	1.57 (0.14)	1.57 (0.14)	1.57 (0.14)	1.57 (0.14)	1.57 (0.14)
4	20 cM	0.06 (0.02)	0.06 (0.02)	0.06 (0.02)	0.06 (0.02)	0.06 (0.02)	0.06 (0.02)

Mean GENEHUNTER HLOD (HLOD_GH) scores and mean CHROM-WALK HLOD (HLOD_FL) scores, averaged over 100 simulated replicates of the Aipotu population, at a location between markers flanking the trait locus for chromosomes 1 and 3. For chromosome 4, mean HLOD scores are reported at an arbitrary chromosomal position, common to all three marker sets Mset4, Mset16, and MsetAll. GENEHUNTER multipoint scores are calculated on markers available within each data set. CHROM-WALK multipoint scores are calculated only on flanking markers jointly. Standard errors of the means are given in parentheses.

ISSN: 2730-6844