Table 2 Multipoint linkage analysis ordered by number of tagSNPs for the chromosome 21 region.
From: Identification of tag single-nucleotide polymorphisms in regions with varying linkage disequilibrium
| Â | # of SNPs | LOD score (p-value) simulated trait (chromosome 21) rs2835626 | LOD Score (p-value) simulated trait (chromosome 20) tsc0041859 | Mean information content |
|---|---|---|---|---|
SNPtagger/HTSNP a | 4 | 11.44 (<0.00001) | 0.03 (0.4) | 0.58 |
Nyholt | 5 | 11.70 (<0.00001) | 0.17 (0.2) | 0.60 |
TagSNP | 5 | 12.03 (<0.00001) | 0.15 (0.2) | 0.60 |
Haploview | 6 | 12.42(<0.00001) | 0.30 (0.12) | 0.62 |
HB Finder | 7 | 12.63 (<0.00001) | 0.80 (0.03) | 0.61 |
Mengb | 8 | 13.27 (<0.00001) | 1.08 (0.013) | 0.60 |
All SNPs | 17 | 13.50(<0.00001) | 0.86 (0.02) | 0.69 |