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Table 4 Variation interval of the disease allele frequency q

From: Modeling the effect of a genetic factor for a complex trait in a simulated population

 

95% Variation interval [range]a

No. Families

No uncertainty

Uncertainty

100

0.24 [0.01; 0.74]

0.24 [0.01; 0.74]

200

0.22 [0.01; 0.54]

0.22 [0.01; 0.55]

500

0.20 [0.07; 0.35]

0.20 [0.01; 0.35]

  1. a 95% variation interval of the disease allele frequency q when the marker allele frequencies are known ("no uncertainty") and when they are estimated from the untransmitted parental alleles ("uncertainty").
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BMC Genomic Data

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