Table 4 Putative candidate genes in candidate QTL regions for inguinal and scrotal hernias. The most promising regions on SSC1, SSC2, SSC5, SSC6, SSC7, SSC15 and SSC17 are shown, as well as the homologous regions in human.
From: Genome-wide linkage analysis of inguinal hernia in pigs using affected sib pairs
QTL region1 | Homologous regions in human2 | Putative candidate genes |
|---|---|---|
SSC1 p25 – q14 | HSA6 q25 | Collagen typeIXα (COL9A1), Estrogen receptor 1 (ESR1) |
HSA18 p11.2 – p11.32 | ||
SSC2 p14 – q23 | HSA5 q12 – q35 | |
HSA11 q13 – p15 | Calcitonin gene-related peptide (CGRP) | |
HSA19 p13.1 – p13.3 | Insulin like hormone 3 (INSL3), Mullerian-inhibiting substance (MIS) | |
SSC5 q11 – q22 | HSA12 q11.2 – p13 | Collagen type II (COL2A1) |
SSC6 q27 – q32 | HSA1 p22 – p36.3 | Insulin-like hormone 5 (INSL5) |
HSA18 q12 – p11.32 | ||
SSC7 q11 – q15 | HSA15 q12 – q26 | Cytochrome P450, family19A1 (CYP19A1) |
SSC7 q24 – q26 | HSA14 q11.2 – q32 | |
SSC15 | HSA2 q11.2 – q21 | |
SSC17 p11 and p21 | HSA5 and HSA20 |