Table 1 Type 1 error rate comparisons based on 5000 simulations of 100 sib pairs under two different types of null models. Null model A is the model simulated under no heritability due to the testing QTL and no polygenic heritability. Null model B is the model without heritability due to the testing QTL but with polygenic heritability h² and ${\sigma }_{a2}^2$ = 1. The other underlying parameters are (β₀, β₁, β₂) = (1, 1, 1), and (σ², α) = (7, 0.5). The assumed s(t) is labeled as "i" for s₀ + s₁t, and "q" for s₀ + s₁t + s₂t².

From: Linkage analysis of longitudinal data and design consideration