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Table 3 Parameter estimates from segregation analysis of residual Apo A1 levels under Class D regressive models, conditional on proband phenotypes

From: Segregation analysis of apolipoprotein A1 levels in families of adolescents: A community-based study in Taiwan

Model Sporadic Familial correlations Environmental Mendelian General
qA [1] [1] 0.974 0.854 0.976
τAA - - =qA [1] 0.971
τAB - - =qA [0.5] 0.989
τBB - - =qA [0] 1.000
AA 118.0 118.4 115.8 118.2 115.9
AB = AA = AA 167.2 114.2 167.3
BB = AA = AA 287.7 195.9 287.8
σ2 492.9 493.2 331.9 390.3 333.3
ρMF [0] 0.240 0.302 0.267 0.301
ρMO [0] 0.129 0.263 0.204 0.266
ρFO [0] 0.081 0.148 0.149 0.148
ρSS [0] 0.000 0.114 0.088 0.115
Parameter # 2 6 9 9 12
-2ln(L) 6453.22 6435.17 6327.62 6361.51 6327.32
AIC 6457.22 6447.17 6345.62 6370.51 6351.32
χ2 125.9 107.85 0.30 34.19 -
P 0.000 0.000 0.960 0.000 -
  1. Abbreviation: #, number of parameters; SEM, standard error of mean; qA, gene frequency; τAA, τAB, τBB, transmission probability; μAA, μAB, μBB, genotype means; σ2, variance; ρMF, ρMO, ρFO, ρSS, correlation coefficients among spouse, mother-offspring, father-offspring and sibling pairs; #, number of parameters; ln(L), logarithm of likelihood; AIC, Akaike information criteria; P, significance level compared with the unrestricted general model.