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Table 3 The power of the proposed test for 500 sibpairs when linkage signal is weak. A diallelic marker is completely linked to the QTL in perfect disequilibrium. The trait value is generated by a QTL with variance of varying size, together with polygenic and common environmental effects (with variance 0.3) and a random individual effect (with variance 0.5).

From: A quantitative linkage score for an association study following a linkage analysis

QTL variance

Fully informative marker

Partially informative marker

 

Linkage

Association-Linkage

Linkage

Association-Linkage

0.03

0.102

0.307

0.083

0.285

0.05

0.148

0.402

0.145

0.475

0.10

0.284

0.666

0.260

0.575

0.20

0.563

0.874

0.520

0.838