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Table 2 Location and frequency of the observed SNP

From: Genetic variants of chemokine receptor CCR7 in patients with systemic lupus erythematosus, Sjogren's syndrome and systemic sclerosis

Position Location SNP Exchange in amino acid? Population Number of subjects carrying the SNP Number of analyzed subjects Allelic frequency (%) Reference
-60 5'-UTR C/T   Systemic sclerosis 1 100 0.50 this work
     SLE 0 20 0.00  
     Sjogren's syndrome 0 40 0.00  
     Controls 0 40 0.00  
+6,476 exon 2 A/G methionine to valine Systemic sclerosis 4 100 2.00 this work
     SLE 0 20 0.00  
     Sjogren's syndrome 1 40 1.25  
     Controls 2 40 2.50  
+6,555 intron 2 C/T   Systemic sclerosis 6 100 3.00 this work
     SLE 2 20 5.00  
     Sjogren's syndrome 3 40 3.75  
     Controls 4 40 5.00  
+6,560 intron 2 C/T   Systemic sclerosis 4 100 2.00 rs3136689
     SLE 0 20 0.00 (HapMap)
     Sjogren's syndrome 0 40 0.00  
     Controls 2 40 2.50  
+10,440 exon 3 A/G no exchange Systemic sclerosis 2 100 1.00 rs2229095
     SLE 0 20 0.00 (HapMap)
     Sjogren's syndrome 1 40 1.25  
     Controls 0 40 0.00  
+11,475 3'-UTR C/A   Systemic sclerosis 1 100 0.50 this work
     SLE 0 20 0.00  
     Sjogren's syndrome 0 40 0.00  
     Controls 0 40 0.00  
  1. Positions of the observed SNP are given relative to the first base coding for the Methionine of exon 1 which has been set to position +1 and the preceding base to -1. SNP, single nucleotide polymorphism. The most frequent allele is named first.